MITOCHONDRIA-TARGETED TETRAPEPTIDE

EPRETIDE

SS-31 · MTP-131 · ELAMIPRETIDE · 10 MG

Epretide™ is elamipretide (SS-31, MTP-131), an aromatic-cationic Szeto-Schiller tetrapeptide that concentrates in the inner mitochondrial membrane and binds cardiolipin. Supplied as lyophilised powder in vials of 10 mg, packed 3 vials per foil sachet for wholesale distribution.

FOR EXPORT ONLY FOR RESEARCH AND ANALYTICS ONLY
Epretide elamipretide SS-31 10 mg sachet label, 3 vials per sachet

ABOUT EPRETIDE

The cardiolipin-binding peptide SS-31

Elamipretide (SS-31, MTP-131) is a synthetic tetrapeptide of the Szeto-Schiller series, built on an alternating aromatic-cationic motif (D-Arg-Dmt-Lys-Phe-NH₂). This structure lets it cross cell membranes independently of receptors and transporters and concentrate more than a thousand-fold in the inner mitochondrial membrane.

There it binds cardiolipin, the phospholipid unique to the inner mitochondrial membrane, stabilising cristae architecture and the electron transport chain. Epretide™ supplies elamipretide as a defined, batch-documented reference material with identity and purity verified on every lot.

4AA

SZETO-SCHILLER TETRAPEPTIDE

10 MG

PER VIAL

2–8°C

COLD CHAIN

DNA double helix illustration representing mitochondria-targeted peptide research

RESEARCH BACKGROUND

The most advanced mitochondria-targeted peptide

First described by Szeto and Schiller, SS-31 became the reference compound of the cardiolipin-protective class: by binding cardiolipin it preserves cristae structure, supports electron transport chain supercomplexes, improves ATP synthesis and reduces excess reactive oxygen species in stressed mitochondria.

Under the name elamipretide, the compound has been taken into clinical development for primary mitochondrial myopathy, Barth syndrome and dry age-related macular degeneration — making it one of the most extensively studied mitochondria-targeted agents in the literature.

PRIMARY REFERENCE

Szeto HH. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol. 2014;171(8):2029–2050.

Weill Cornell Medical College

DOI: 10.1111/BPH.12461

Reference provided for scientific context only. Epretide™ is analytical grade, for research and analytics only, and is not a medicinal product or dietary supplement. CoreyPauling is not affiliated with the cited authors.

PRODUCT SPECIFICATIONS

Epretide™ at a glance

Product name Epretide™
Active substance Elamipretide (SS-31, MTP-131) — mitochondria-targeted tetrapeptide
Strength 10 mg per vial
Form Lyophilised powder for reconstitution
Presentation Multi-dose glass vial
Pack size 3 vials per foil sachet
Origin Synthetic Szeto-Schiller tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂)
Storage Store cold at 2–8°C; stable refrigerated for full shelf life, near-stable over 90 days at room temperature
Intended use Analytical grade · For research and analytics only · For export only
Documentation Batch-specific Certificate of Analysis

OUR TECHNOLOGY

Pressurized Dark-Room Fragmented Lyophilization

Epretide™ is lyophilised using CoreyPauling's proprietary Pressurized Dark-Room Fragmented Lyophilization process, which protects the peptide from light and oxidative stress during freeze-drying — critical for a short tetrapeptide whose value lies in its intact aromatic-cationic sequence. The result is stability that conventional lyophilisates cannot match.

90+ days

Near-stable at room temperature

The lyophilised powder remains almost fully stable for over 90 days at room temperature — forgiving of transit delays and customs holds without loss of integrity.

3 years

Stable in cold storage

Stored cold at 2–8°C, Epretide™ retains full stability for the shelf life stated on every label, from the date of manufacture.

Epretide™ is analytical grade only. CoreyPauling does not encourage or support its use in humans or veterinary applications.

QUALITY & MANUFACTURING

Every batch documented

STD

International standards

Manufactured under internationally recognised quality standards with controlled environments and validated processes at every production step.

HPLC

Analytical verification

Identity, purity and content are verified by HPLC and complementary analytical methods before any batch is released.

LOT

Full traceability

Lot, manufacturing and expiry data are printed on every sachet and vial, tied to batch records and the Certificate of Analysis.

STORAGE & HANDLING

Cold chain, door to door

Store cold at 2–8°C

Keep refrigerated for full shelf life. Do not freeze. Protect vials from light and keep them in the original sachet until use; brief room-temperature excursions are tolerated thanks to our lyophilization process.

Insulated export shipping

Wholesale consignments ship in insulated packaging with cooling elements and temperature indicators, with export documentation prepared per destination.

FAQ

Frequently Asked Questions

Epretide™ is available exclusively through authorized retailers and distributors. Contact our wholesale team to be directed to an authorized retailer in your region.

No. CoreyPauling supplies wholesale quantities to distributors and authorized retailers only.

MOQ depends on destination and packaging configuration. Standard wholesale units are sachets of 3 vials; contact us with your required volume for tiered pricing.

Yes. Every batch ships with a batch-specific Certificate of Analysis covering identity, purity and content, referenced to the lot number printed on the sachet and vial labels.

Commercial invoice, packing list and Certificate of Analysis are standard. Additional documentation can be prepared according to the import requirements of the destination country.

CoreyPauling laboratory and lyophilization facility

ABOUT COREYPAULING

Science · Innovation · Quality · Trust

CoreyPauling is a US–Singapore based biotechnology company developing and supplying research-grade peptides and proteins to distributors and laboratories worldwide. Grounded in scientific rigour and international manufacturing standards, the brand stands for precision, continuous innovation and long-term reliability.

Epretide™ sits alongside the wider CoreyPauling catalogue — including Somapin™, Bepeci™, Retatride™, Tesamore™, Thymob™, Lorenpickart™, Kaypv™, Menotrope™, Igtrin™, Glutatone™ and Pregnil™ — all supplied under the same documentation and cold-chain standards.

Every batch of Epretide™ is manufactured at the CoreyPauling facility. Full company information, the complete product catalogue and manufacturing capabilities are available on the official factory website at coreypauling.com.

VISIT COREYPAULING.COM

WHOLESALE INQUIRY

Distribute Epretide™

For quotations, batch documentation, certificates of analysis and export terms, contact our wholesale team. Please include your company details, destination country and required quantities.

support@coreypauling.com
For Research and Analytics Only